Spanking Lupus Link [2021] | EXCLUSIVE • 2025 |

Spanking and other forms of physical discipline fall under the umbrella of Adverse Childhood Experiences (ACEs).

Lead author Dr. Kimberly DeQuattro noted, "More than half of the participants with lupus reported ACE exposure... There is a clear difference in patient-reported outcomes with cumulative ACE exposure in these individuals". This suggests that past trauma can make the disease itself much more difficult to live with.

indicate that Adverse Childhood Experiences (ACEs), which include frequent physical punishment, are associated with higher rates of autoimmune diseases. The "Link" Mechanism spanking lupus link

Research indicates that severe childhood physical and emotional trauma significantly increases the risk of developing systemic lupus erythematosus (SLE) in adulthood by causing chronic inflammation and immune system dysregulation. Studies, including the Nurses' Health Study II, found that women with high levels of childhood abuse were more than twice as likely to develop lupus. Learn more about the study findings from CreakyJoints .

Chronic stress elevates systemic levels of pro-inflammatory cytokines, specifically and Tumor Necrosis Factor-alpha (TNF- Spanking and other forms of physical discipline fall

The influence of childhood adversity doesn't stop at increasing the risk of getting lupus; it also appears to significantly worsen the course of the disease for those who already have it.

While spanking does not directly "cause" lupus, the biological mechanisms triggered by physical punishment—specifically chronic stress and physical trauma—can act as catalysts for autoimmune flares in genetically predisposed individuals. There is a clear difference in patient-reported outcomes

: Early trauma can lead to chemical "marks" on DNA that alter how genes related to the immune system are expressed, potentially "switching on" a genetic predisposition for lupus. 3. Broad Health Implications

For years, rheumatologists viewed Systemic Lupus Erythematosus (SLE) primarily through a genetic and environmental lens, pointing to triggers like UV light, viral infections, or hormonal shifts. However, large-scale longitudinal cohorts have illuminated a strong psychosocial risk factor: early life adversity.

Chronic stress alters the hypothalamic-pituitary-adrenal (HPA) axis. This system regulates the body's response to stress.